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Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury?
Sponsor: University of Alberta
Summary
This proof-of-principle study will determine if breathing an increased concentration of oxygen above the concentration in normal room air results in changes in the sensory and motor function in people with subacute or chronic, severe spinal cord injury (SCI).
Key Details
Gender
All
Age Range
18 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
25
Start Date
2022-07-11
Completion Date
2026-12-31
Last Updated
2025-08-26
Healthy Volunteers
Yes
Conditions
Interventions
Pure oxygen (99%) from Praxair, Edmonton, DIN# 02014408
Participants will receive oxygen (99%) or room air (placebo) delivered through a face mask at a flow rate of 10 litres/min for 2 minutes. The participants will be exposed twice to both conditions over 4 experiments at a minimum of 2 week intervals between each testing session.
Locations (1)
University of Alberta, Clinical Sciences Bldg
Edmonton, Alberta, Canada