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Nuclear Imaging for Subtype Diagnosis of Primary Aldosteronism
Sponsor: University of Calgary
Summary
This study is to evaluate the accuracy of a novel radiopharmaceutical tracer, para-chloro-2-\[18F\]fluoroethyl etomidate (CETO), used with positron emission tomography (PET) and computed tomography (CT), as a way to subtype unilateral vs. bilateral forms of Primary Aldosteronism, compared to AVS as a reference gold standard.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2023-01-01
Completion Date
2026-06-30
Last Updated
2024-07-24
Healthy Volunteers
No
Conditions
Interventions
[18-F]CETO
PET/CT will be performed; Non-contrast CT images will be acquired over the adrenals (slice width, \~3 mm). CETO (\~2.5 MBq/kg; up to 365 MBq +/- 20%) will be administered as a single dose intravenously and dynamic PET images will be acquired from \~0-90 minutes.
Locations (1)
University of Calgary
Calgary, Alberta, Canada