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RECRUITING
NCT05474846
PHASE2/PHASE3

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

Sponsor: M.D. Anderson Cancer Center

View on ClinicalTrials.gov

Summary

To learn if Cognitive Behavior Therapy (called CBT), combined with either Bright Light Therapy (called BLT), methylphenidate, and/or melatonin, can help improve sleep and other related symptoms such as fatigue, anxiety, and depression in cancer patients. This is an investigational study. In this study, BLT, Methylphenidate and Melatonin will be compared to their placebos.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

188

Start Date

2022-11-21

Completion Date

2027-02-28

Last Updated

2025-11-06

Healthy Volunteers

No

Interventions

DRUG

Melatonin

Given by PO

OTHER

Placebo for Melatonin

Given by PO

DRUG

Melatonin

Given by PO

DRUG

Methylphenidate

Given by PO

Locations (1)

MD Anderson Cancer Center

Houston, Texas, United States