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Blood Biomarkers in Pediatric Kidney Transplant Recipients
Sponsor: University of Minnesota
Summary
The objective of the proposed study is to assess whether a blood biomarker can be used to monitor the response to rejection treatment in pediatric kidney transplant recipients with biopsy-proven acute cellular or antibody mediated rejection. The study hypothesizes that blood gene expression profile and donor-derived cell-free DNA biomarkers (omnigraf) can be used to predict acute rejection and monitor its response to treatment.
Official title: Use of Blood Gene Expression Profile and Donor-derived Cell-free DNA to Monitor Response to Treatment After Biopsy-proven Acute Rejection in Pediatric Kidney Transplant Recipients
Key Details
Gender
All
Age Range
Any - 21 Years
Study Type
OBSERVATIONAL
Enrollment
27
Start Date
2023-08-21
Completion Date
2026-11-01
Last Updated
2025-12-17
Healthy Volunteers
No
Conditions
Interventions
Observational group
Includes blood draws and data collection only
Locations (1)
University of Minnesota
Minneapolis, Minnesota, United States