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ACTIVE NOT RECRUITING
NCT05477823
EARLY_PHASE1

Imaging and Genomic Biomarkers to Predict Response in Prostate Cancer

Sponsor: University of Wisconsin, Madison

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate the imaging and gene expression biomarkers in prostate cancer. Participants have high-risk prostate cancer and have indicated they will undergo external beam radiation therapy, brachytherapy, and androgen deprivation therapy (EBRT+BTX+ADT). Participants can expect to be in this study for up to 5 years.

Official title: Pilot Study to Identify Radiogenomic Biomarkers to Predict Early Treatment Response to Androgen Deprivation Therapy and Radiation Therapy in High Risk Prostate Cancer

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2023-03-08

Completion Date

2027-08

Last Updated

2026-03-20

Healthy Volunteers

No

Conditions

Interventions

RADIATION

External beam radiation therapy

Standard of care EBRT

RADIATION

Prostate brachytherapy boost

Standard of care BTX

DRUG

Androgen deprivation therapy

Standard of care ADT

DIAGNOSTIC_TEST

Positron emission tomography (PET)/magnetic resonance imaging (MRI)

Pelvic PET scanning with tracer will take approximately 45 minutes. This will be followed by the injection of a contrast agent followed by whole body PET/MRI scanning which will take approximately 30 minutes.

Locations (1)

University of Wisconsin

Madison, Wisconsin, United States