Clinical Research Directory
Browse clinical research sites, groups, and studies.
LITMUS Imaging Study
Sponsor: University of Oxford
Summary
The LITMUS Imaging Study is a prospectively recruited, observational study of patients with histologically characterised non-alcoholic fatty liver disease (NAFLD). It aims to evaluate the diagnostic performance of imaging biomarkers (ultrasound elastography and magnetic resonance biomarkers) against NAFLD histological scores in a cross-sectional analysis and the natural history of NAFLD in a longitudinal study.
Official title: Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS): Assessment & Validation of Imaging Modality Performance Across the NAFLD Spectrum in a Prospectively Recruited Cohort
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
450
Start Date
2019-09-04
Completion Date
2025-10-31
Last Updated
2025-04-16
Healthy Volunteers
No
Locations (18)
Pinnacle Clinical Research
San Antonio, Texas, United States
Helsinki University Hospital
Helsinki, Finland
Le Centre de Recherche Clinique (CRC) du CHU d'Angers
Angers, France
Institut ICAN - Institute of Cardiometabolism And Nutrition Hôpital de la Pitié Salpêtrière
Paris, France
UNIVERSITÄTSMEDIZIN der Johannes Gutenberg Universität Mainz
Mainz, Germany
Universitätsklinikums Würzburg
Würzburg, Germany
Laiko General Hospital of Athens
Athens, Greece
Università di Palermo
Palermo, Italy
Department of Medical Sciences University of Torino
Torino, Italy
Vall d'Hebron University Hospital
Barcelona, Spain
Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocío University Hospital
Seville, Spain
HU Clínico de Valladolid
Valladolid, Spain
Linköping University Hospital
Linköping, Sweden
Inselspital, University Hospital
Bern, Switzerland
Addenbrookes Hospital
Cambridge, United Kingdom
The Newcastle Upon Tyne Hospitals Nhs Foundation Trust
Newcastle upon Tyne, United Kingdom
Queens Medical Centre
Nottingham, United Kingdom
Oxford University Hospitals NHS Foundation Trust
Oxford, United Kingdom