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ACTIVE NOT RECRUITING
NCT05479721

LITMUS Imaging Study

Sponsor: University of Oxford

View on ClinicalTrials.gov

Summary

The LITMUS Imaging Study is a prospectively recruited, observational study of patients with histologically characterised non-alcoholic fatty liver disease (NAFLD). It aims to evaluate the diagnostic performance of imaging biomarkers (ultrasound elastography and magnetic resonance biomarkers) against NAFLD histological scores in a cross-sectional analysis and the natural history of NAFLD in a longitudinal study.

Official title: Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS): Assessment & Validation of Imaging Modality Performance Across the NAFLD Spectrum in a Prospectively Recruited Cohort

Key Details

Gender

All

Age Range

18 Years - 100 Years

Study Type

OBSERVATIONAL

Enrollment

450

Start Date

2019-09-04

Completion Date

2025-10-31

Last Updated

2025-04-16

Healthy Volunteers

No

Locations (18)

Pinnacle Clinical Research

San Antonio, Texas, United States

Helsinki University Hospital

Helsinki, Finland

Le Centre de Recherche Clinique (CRC) du CHU d'Angers

Angers, France

Institut ICAN - Institute of Cardiometabolism And Nutrition Hôpital de la Pitié Salpêtrière

Paris, France

UNIVERSITÄTSMEDIZIN der Johannes Gutenberg Universität Mainz

Mainz, Germany

Universitätsklinikums Würzburg

Würzburg, Germany

Laiko General Hospital of Athens

Athens, Greece

Università di Palermo

Palermo, Italy

Department of Medical Sciences University of Torino

Torino, Italy

Vall d'Hebron University Hospital

Barcelona, Spain

Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocío University Hospital

Seville, Spain

HU Clínico de Valladolid

Valladolid, Spain

Linköping University Hospital

Linköping, Sweden

Inselspital, University Hospital

Bern, Switzerland

Addenbrookes Hospital

Cambridge, United Kingdom

The Newcastle Upon Tyne Hospitals Nhs Foundation Trust

Newcastle upon Tyne, United Kingdom

Queens Medical Centre

Nottingham, United Kingdom

Oxford University Hospitals NHS Foundation Trust

Oxford, United Kingdom