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Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combin
Sponsor: Case Comprehensive Cancer Center
Summary
Unintentional weight loss (UWL) is commonly associated with a wide variety of diseases and there is still no valid diagnostic pathway for evaluating UWL. When detecting UWL coupled with GRAIL Galleri testing, (an investigational pan-cancer early detection test), it is thought that there is a greater positive predictive value in detecting malignancies. This study aims to test the potential synergistic effects of UWL detection and GRAIL usage to detect malignancy at an even earlier rate. UWL will be measured using weekly weight tracking.
Official title: Unintentional Weight Loss and Cancer: A Prospective Trial of Patient-centered Weight Tracking Combined With GRAIL Galleri Testing to Improve Early Detection
Key Details
Gender
All
Age Range
40 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
1000
Start Date
2023-05-05
Completion Date
2027-01-01
Last Updated
2026-02-19
Healthy Volunteers
No
Conditions
Interventions
GRAIL Galleri
A blood test that aims to detect cancers earlier by looking for abnormal DNA shed from cancer cells into the blood.
Locations (1)
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
Cleveland, Ohio, United States