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MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)
Sponsor: Aristotle University Of Thessaloniki
Summary
MiECS is one of the largest multicentre randomised controlled trials on extracorporeal circulation conducted under the auspices of Minimal Invasive Extracorporeal Technologies International Society (MiECTiS). It is designed to ultimately address the emerging effectiveness of MiECC systems in the light of modern perfusion practice worldwide. The primary hypothesis is that MiECC, as compared to conventional CPB (cCPB), reduces the proportion of patients experiencing serious perfusion-related postoperative morbidity after cardiac surgery. The study will be led by the Clinical Research Unit of the Special Unit for Biomedical Research and Education (SUBRE), Aristotle University of Thessaloniki School of Medicine in Greece (AUSoM) with Chief Investigator Professor Kyriakos Anastasiadis, who is a key-opinion-leader in the field of MiECC, founder and Executive Board of MiECTiS.
Official title: Minimally Invasive Extracorporeal Circulation Versus Conventional Cardiopulmonary Bypass in Patients Undergoing Cardiac Surgery (MiECS): a Randomised Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
INTERVENTIONAL
Enrollment
1300
Start Date
2022-05-26
Completion Date
2029-03-31
Last Updated
2026-03-30
Healthy Volunteers
No
Interventions
Minimal Invasive Extracorporeal Circulation
Cardiac surgery with Minimal Invasive Extracorporeal Circulation (MiECC).
Conventional cardiopulmonary bypass
Cardiac surgery with conventional cardiopulmonary bypass (cCPB).
Locations (13)
Perfusion Services University Health Network, Toronto General Hospital
Toronto, Canada
Department of Cardiac Surgery
Coswig, Germany
Department of Thoracic and Cardiovascular Surgery, University Medical Centre Goettingen
Göttingen, Germany
Department of Cardiothoracic and Vascular Surgery, Ulm University Hospital
Ulm, Germany
Cardiothoracic Department AHEPA University Hospital
Thessaloniki, Greece
Department of Cardiac Surgery GVM Anthea Hospital
Bari, Italy
Department of Cardiac Surgery GVM Maria Eleonora Hospital
Palermo, Italy
Department of Cardiovascular Surgery, Ankara City Hospital
Ankara, Turkey (Türkiye)
Department of Cardiovascular Surgery, Izmir Bakırçay University, Faculty of Medicine
Izmir, Turkey (Türkiye)
Department of Cardiovascular Surgery, Faculty of Medicine, Recep Tayyip Erdoğan University
Rize, Turkey (Türkiye)
Department of Cardiac Surgery, Royal Papworth Hospital
Cambridge, United Kingdom
Deparment of Cardiac Surgery, Castle Hill Hospital
Hull, United Kingdom
Department of Cardiothoracic Surgery, Hammersmith Hospital
London, United Kingdom