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Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy
Sponsor: University of Minnesota
Summary
Deep brain stimulation (DBS) is used to treat epilepsy in cases where patients are medically refractory and are not candidates for surgical resection. This therapy has been shown to be effective in seizure reduction, yet very few patients achieve the ultimate goal of seizure freedom. Implantable neural stimulators (INSs) have many parameters that may be adjusted, and could be tuned to achieve very patient specific therapies. This study will develop a platform for stimulation setting optimization based on power spectral density (PSD) measures.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2023-09-15
Completion Date
2030-01-15
Last Updated
2025-10-24
Healthy Volunteers
No
Interventions
PS and OS stimulation order 1
PS, OS, OS
PS and OS stimulation order 2
OS, PS, OS
PS and OS stimulation order 3
OS, OS, PS
Locations (1)
University of Minnesota
Minneapolis, Minnesota, United States