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COMPLETED
NCT05494645
PHASE4

Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery

Sponsor: St. Luke's Hospital, Pennsylvania

View on ClinicalTrials.gov

Summary

Liposomal Bupivacaine (Exparel) has been recently studied as the active agent utilized in various nerve block. Due to its liposomal form allowing for extended delivery, Exparel has been used in various peri-operative nerve blocks among multiple orthopaedic specialties in hopes of achieving improved pain control and decreased opioid use. This study compares the efficacy and effect on opioid use of peripheral nerve blocks and local infiltration with and without Exparel in patients undergoing foot and ankle surgery.

Official title: Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery: A Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

248

Start Date

2022-03-01

Completion Date

2023-01-31

Last Updated

2026-04-28

Healthy Volunteers

No

Interventions

DRUG

Exparel

Liposomal bupivicaine

DRUG

Peripheral Nerve Block

Peripheral nerve block without Exparel

Locations (1)

St. Luke's University Health Network

Bethlehem, Pennsylvania, United States