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ENROLLING BY INVITATION
NCT05497219
NA

Reference Values for Videofluoroscopic Measures of Swallowing

Sponsor: University Health Network, Toronto

View on ClinicalTrials.gov

Summary

Dysphagia (swallowing impairment) is a serious health condition seen in many age-related disease and injury processes. Although videofluoroscopy (VF) is an international "gold standard" dysphagia diagnostic exam, there is a paucity of available normative physiologic VF reference values in healthy adults across the age span to guide interpretation of these examinations. In this project, the investigators will extend previous work on the quantitative measurement of swallowing physiology from VF examinations to establish reference values for swallowing in healthy adults, and to identify clinical decision point values for differentiating healthy swallowing across the age span from disordered swallowing in several high-risk clinical populations to study dysphagia.

Official title: Establishing Reference Values and Clinical Decision Points for Quantitative Videofluoroscopic Measures of Swallowing

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

580

Start Date

2022-11-15

Completion Date

2027-07-31

Last Updated

2025-10-08

Healthy Volunteers

Yes

Interventions

DIAGNOSTIC_TEST

Videofluoroscopic Swallowing Study (VF)

A videofluoroscopy (VF) is a dynamic radiological evaluation of swallowing in which the participant swallows liquid or food boluses of different consistencies prepared with barium contrast. The x-rays are recorded at 30 frames per second.

Locations (5)

University of Florida

Gainesville, Florida, United States

University of Cincinnati Medical Center

Cincinnati, Ohio, United States

The Ohio State University

Columbus, Ohio, United States

McMaster University

Hamilton, Ontario, Canada

University Health Network

Toronto, Ontario, Canada