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Interrogating Fatty Acid Metabolism Impairment and Clinical Correlates in Males with Klinefelter Syndrome
Sponsor: University of Colorado, Denver
Summary
This study will learn more about how the body uses energy. Usually, the body uses sugars as energy first and then fats are used when the sugar stores are gone. Some people have trouble using fats as energy. This can lead to feeling tired, difficulty exercising, and storing too much fat where it does not belong (like in the muscle). It is believed that some boys and men with Klinefelter Syndrome may not be able to use fats as energy normally, and that a medication called fenofibrate could help this.
Key Details
Gender
MALE
Age Range
15 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
44
Start Date
2022-11-03
Completion Date
2025-08-30
Last Updated
2024-10-16
Healthy Volunteers
Yes
Conditions
Interventions
Fenofibrate 145 mg
Fenofibrate 145 mg PO daily for 4 weeks
Locations (1)
University of Colorado - Anschutz Medical Campus
Aurora, Colorado, United States