Clinical Research Directory

Interscalene Brachial Plexus Block and Early Wound-Related Symptoms After Open Rotator Cuff Repair

Sponsor: Yuzuncu Yil University

Summary

This randomized controlled trial evaluated the association of interscalene brachial plexus block (ISB) with early postoperative wound-related symptom scores and perioperative biomarker responses in patients undergoing open rotator cuff repair. Participants were randomly allocated to receive either ultrasound-guided interscalene brachial plexus block or standardized general anaesthesia. The primary outcome was postoperative wound-related assessment using the Toronto Symptom Assessment System for Wounds (TSAS-W) on postoperative days 5 and 14. Secondary outcomes included perioperative serum cytokine and growth-factor concentrations (IL-1β, IL-2, TNF-α, EGF, PDGF, and TGF-β), platelet counts, postoperative pain scores, tramadol consumption within 48 hours, time to mobilisation, and postoperative nausea and vomiting. This exploratory study aimed to investigate whether interscalene brachial plexus block was associated with differences in perioperative biological responses and early postoperative wound-related symptom scores compared with general anaesthesia.

Official title: Interscalene Brachial Plexus Block is Associated With Lower Patient-Reported Wound Symptom Scores and Altered Perioperative Biomarker Profiles Following Open Rotator Cuff Repair: An Exploratory Randomised Controlled Trial

Key Details

Conditions

Interventions

Locations (1)