Clinical Research Directory

Inclusion Criteria: * (1) Age 18-60 years old, regardless of gender; * (2) Blood pressure conditions meet one of the following: 1) Office blood pressure ≥ 140/90mmHg; 2) Ambulatory blood pressure monitoring whole day blood pressure \> 130/80 mmHg or daytime blood pressure \> 135/85 mmHg; * (3) After strict drug elution, it met the diagnostic criteria of primary aldosteronism, and bilateral primary aldosteronism was confirmed by adrenal venous sampling; * (4) No surgical intent or contraindication to surgery and willing to undergo pharmacological treatment or percutaneous superselective adrenal artery embolization; * (5) The patient or his/her legal representative shall sign the written informed consent approved by the ethics committee before the screening. Exclusion Criteria: * (1) Primary hypertension or secondary hypertension with other causes; * (2) A woman who is pregnant or lactating, or has a birth plan for the next year; * (3) There are serious organic diseases, especially liver and kidney dysfunction(eGFR\<45 mL/min/1.73 m2); * (4) Severe allergy to contrast medium; * (5) Other serious organic diseases, life expectancy \< 12 months; * (6) Adrenal CT showed adenoma.; * (7) Patients are enrolled or want to participate in other clinical studies. During the enrollment study, the results of this study will be affected.