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Ansa Cervicalis and Hypoglossal Nerve Stimulation in OSA
Sponsor: Vanderbilt University Medical Center
Summary
Polysomnography (PSG) and drug-induced sleep endoscopy (DISE) are widely used diagnostic studies for assessing obstructive sleep apnea (OSA) severity and collapse patterns of the upper airway anatomy during sleep. Hypoglossal nerve stimulation (HNS) therapy for obstructive sleep apnea suffers from variable response at the level of the soft palate. The Investigators propose a study examining the physiologic effect of ansa cervicalis stimulation (ACS) alone and in combination with HNS during PSG and DISE.
Official title: Ansa Cervicalis and Hypoglossal Nerve Stimulation in Obstructive Sleep Apnea
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2022-11-03
Completion Date
2026-11-30
Last Updated
2025-10-15
Healthy Volunteers
No
Conditions
Interventions
Grass S88 Muscle Stimulator
The Grass S88 nerve and muscle stimulator is a widely-used tool in electromyography and nerve conduction studies. During the DISE and second sleep study, fine-wire electrodes will be placed into the hypoglossal nerve or genioglossus muscle. Two more electrodes are placed transcutaneously, proximate to the bilateral branches of the cervicalis innervating the sternothyroid muscle in the anterior neck.
Locations (1)
Vanderbilt University Medical Center
Nashville, Tennessee, United States