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The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer
Sponsor: Thomas Jefferson University
Summary
This clinical trial compares the effect of pulmonary vein-first surgical technique to pulmonary artery-first surgical technique in decreasing circulating tumor cell deoxyribonucleic acid (ctDNA) in patients with stage I-III non-small cell lung cancer. Pulmonary vein first and pulmonary artery first surgical techniques are standard surgical techniques for the division of the blood vessels during lung resection surgery. Pulmonary vein-first surgical technique may reduce the risk of shedding tumor cells during surgery and influence long term overall survival.
Official title: The Impact of Surgical Technique on Circulating Tumor DNA in Early-Stage Non-Small Cell Lung Cancer
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2022-08-31
Completion Date
2029-01-01
Last Updated
2026-01-23
Healthy Volunteers
No
Conditions
Interventions
Pulmonary Artery-First Surgical Technique
Undergo pulmonary artery first surgical technique
Biospecimen Collection
Correlative studies
Locations (4)
Abington Memorial Hospital
Abington, Pennsylvania, United States
Jefferson Health Northeast
Philadelphia, Pennsylvania, United States
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States
Asplundh Cancer Pavilion at Jefferson Health
Willow Grove, Pennsylvania, United States