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RECRUITING
NCT05502523
NA

The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

Sponsor: Thomas Jefferson University

View on ClinicalTrials.gov

Summary

This clinical trial compares the effect of pulmonary vein-first surgical technique to pulmonary artery-first surgical technique in decreasing circulating tumor cell deoxyribonucleic acid (ctDNA) in patients with stage I-III non-small cell lung cancer. Pulmonary vein first and pulmonary artery first surgical techniques are standard surgical techniques for the division of the blood vessels during lung resection surgery. Pulmonary vein-first surgical technique may reduce the risk of shedding tumor cells during surgery and influence long term overall survival.

Official title: The Impact of Surgical Technique on Circulating Tumor DNA in Early-Stage Non-Small Cell Lung Cancer

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2022-08-31

Completion Date

2029-01-01

Last Updated

2026-01-23

Healthy Volunteers

No

Interventions

PROCEDURE

Pulmonary Artery-First Surgical Technique

Undergo pulmonary artery first surgical technique

PROCEDURE

Biospecimen Collection

Correlative studies

Locations (4)

Abington Memorial Hospital

Abington, Pennsylvania, United States

Jefferson Health Northeast

Philadelphia, Pennsylvania, United States

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, United States

Asplundh Cancer Pavilion at Jefferson Health

Willow Grove, Pennsylvania, United States