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RECRUITING
NCT05503667
PHASE2

Neoadjuvant Furmonertinib Plus Bevacizumab or Furmonertinib Monotherapy for Resectable and Potentially Resectable Stage III-IVA EGFR Mutation-Positive Lung Adenocarcinoma

Sponsor: Shanghai Pulmonary Hospital, Shanghai, China

View on ClinicalTrials.gov

Summary

To explore the efficacy and safety of neoadjuvant furmonertinib combined with bevacizumab in the treatment of resectable and potentially resectable stage III-IVA EGFR mutation-positive lung adenocarcinoma.

Official title: Neoadjuvant Furmonertinib Plus Bevacizumab or Furmonertinib Monotherapy for Resectable and Potentially Resectable Stage III-IVA EGFR Mutation-Positive Lung Adenocarcinoma: A Randomized, Controlled, Open-label, Single-center Phase II Clinical Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

96

Start Date

2022-02-01

Completion Date

2028-12-31

Last Updated

2022-08-17

Healthy Volunteers

No

Interventions

DRUG

Furmonertinib

Furmonertinib 80 mg/day for 16 weeks

DRUG

Bevacizumab

bevacizumab 400 mg/4 weeks i.v. for 4 times

Locations (1)

Shanghai Pulmonary Hospital

Shanghai, Shanghai Municipality, China