Clinical Research Directory

Inclusion Criteria: * Body mass index (BMI) greater than 30 kg/m2, who are eligible for ESG * Patients scheduled to undergo an endoscopic bariatric weight loss procedure (ESG) * Patients older than 18 years and younger than 75 years of age at the time of consent * Patients able to provide written informed consent on the Institutional review board (IRB) approved informed consent form * Patients willing and able to comply with study requirements for follow-up Exclusion criteria: * Patients who are treated with intragastric balloons * Family history of esophageal, gastric, or duodenal malignancy and active gastric ulceration, * Pre-existing esophageal stenosis/stricture preventing the advancement of an endoscope during screening/baseline Esophagogastroduodenoscopy (EGD) * Presence of any gastric condition which required endoscopic surveillance (e.g., known gastric intestinal metaplasia), * Known vascular abnormalities, obligate therapeutic anticoagulation, and pregnancy/lactation * Evidence of end-stage liver disease, including portal hypertension, ascites, and coagulopathy * Positivity for hepatitis B virus or hepatitis C virus, current alcohol consumption of more than 20 g/day in females and more than 30 g/day in males on average, use of medications with reported hepato-steatogenic effect (amiodarone, tamoxifen, estrogens), and drug-induced liver disease * Type 1 diabetes, Prior bariatric surgery, Autoimmune liver disease (antinuclear antibody titer \>1/160), Wilson's disease, hemochromatosis, alpha1-antitrypsin deficiency, * Known positivity for human immunodeficiency virus, a concomitant disease with reduced life expectancy, severe psychiatric condition, drug dependence, or inability to provide informed consent. * The patient refuses or is unable to provide written informed consent * Prior bariatric treatment procedure