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Efficacy of Immunosuppressive Therapy for IgA Nephropathy With Stage 3 or 4 CKD
Sponsor: Air Force Military Medical University, China
Summary
The purpose of this clinical trial is to evaluate the long-term efficacy and safety of low-dose oral corticosteroids combined with cyclophosphamide therapy and low-dose corticosteroids monotherapy, on a background of maximal RAS inhibitor therapy, for IgA nephropathy with stage 3 or 4 chronic kidney disease.
Official title: Efficacy and Safety of Immunosuppressive Therapy for IgA Nephropathy With Stage 3 or 4 Chronic Kidney Disease
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
208
Start Date
2024-02-01
Completion Date
2028-08
Last Updated
2024-05-06
Healthy Volunteers
No
Conditions
Interventions
Prednisolone
RAS blockade as much as tolerated or allowed
Prednisolone plus Cyclophosphamide
RAS blockade as much as tolerated or allowed
Locations (1)
AFMMU
Xi'an, China