Clinical Research Directory

Inclusion Criteria: 1. The patients are referred to colposcopy and biopsy examinations due to abnormal cervical screening results with no precancerous lesions discovered by pathology. 2. The cervical precancerous lesions are highly suspected by clinicians with one or more following risk factors: * The course of HPV type 16/18 persistent infection is more than two years. * The integration reads of HPV is more than 15. * The impression of colposcopy indicates precancerous lesions. * The cervical TCT indicates ASC-H/HSIL/SCC/AGC-FN/AIS/AC. Exclusion Criteria: 1. Pregnant women. 2. Vaginal intraepithelial neoplasia is highly suspected by colposcopy and pathological examinations. 3. The patients are suffering malignant tumors of other system and have not been cured. 4. There is acute inflammation of the lower genital or anal tract. 5. The patients' health will be severely harmed by the colposcopy and cervical conization due to some circumstances such as severe insufficiency of liver and kidney function, blood diseases and acute inflammation of other systems.