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Evaluation of Advanced HIV Disease Differentiated Care Model in Malawi
Sponsor: Elizabeth Glaser Pediatric AIDS Foundation
Summary
This study will evaluate the implementation of an enhanced package of care, CD4 and tuberculosis lipoarabinomannan (TB-LAM) tests and the initiation of patients on TB prophylaxis \[TPT and CPT\], on retention in care and viral suppression ((\<50 copies/ml) at 6 and 12 months after AHD care and treatment enrollment. The study will also assess the change in AHD screening, management and service uptake indicators among PLHIV clients before and after implementation of the QI collaborative implementation (QICI) project, evaluate the acceptability and feasibility of the AHD package of care among patients and HCWs providing related health services, and conduct a cost analysis of implementing the enhanced AHD package of care in a hub-and-spoke implementation of care model.
Official title: Evaluation of Advanced HIV Disease Differentiated Care Model in Malawi: A Mixed Methods Non-randomized Cluster Study
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
700
Start Date
2021-06-01
Completion Date
2024-12-30
Last Updated
2026-09-10
Healthy Volunteers
No
Conditions
Interventions
Enhanced package for AHD care
The enhanced package of AHD care includes CD4 and tuberculosis lipoarabinomannan (TB-LAM) tests and the initiation of patients on TB prophylaxis \[TPT and CPT\], offered through a hub-and-spoke facility system, with continuous quality improvement (QI)
Locations (13)
Mlambe Mission Hospital
Mlambe, Blantyre, Malawi
Chiradzulu District Hospital
Chiradzulu, Chiradzulu, Malawi
Dedza district hospital
Dedza, Dedza, Malawi
Lobi rural hospital
Lobi, Dedza, Malawi
Mua Mission Hospital
Mtakataka, Dedza, Malawi
Kapiri Mission Hospital
Kapiri, Mchinji, Malawi
St Michael's Guilleme Community Hospital
Mchinji, Mchinji, Malawi
Malamulo Mission Hospital
Thyolo, Thyolo, Malawi
Domasi Rural Hospital
Domasi, Zomba, Malawi
Saint Luke's Mission Hospital
Zomba, Zomba, Malawi
Mchinji District Hopsital
Mchinji, Malawi
Ntcheu District Hospital
Ntcheu, Malawi
Sister Theresa Community Hospital
Ntcheu, Malawi