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Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis
Sponsor: Tanta University
Summary
The study aims to compare the potential benefit of allopurinol versus atorvastatin in reducing the risk of developing cirrhosis-related complications, delaying the onset of hepatocellular carcinoma, and improving survival. Furthermore, the study aims to evaluate their impact on parents' related quality of life.
Official title: The Potential Role of Allopurinol Versus Atorvastatin to Prevent Complications of Liver Cirrhosis: A Quadruple Blind Clinical Study
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2022-11-15
Completion Date
2026-01-25
Last Updated
2026-08-11
Healthy Volunteers
No
Interventions
Allopurinol 300 MG
a competitive xanthine oxidase inhibitor, reduces oxidative stress and attenuates bacterial translocation
Atorvastatin 20mg
is lipid-lowering agent with anti-oxidative stress and anti-inflammation properties
Placebo
not containing drugs
Locations (1)
Tanta University
Tanta, Egypt