Clinical Research Directory

Inclusion Criteria: * Patients who are considering undergoing EBT for weight loss * Patients with a BMI \>30 kg/m2 (without obesity related comorbidities) * Patients with a BMI \>27 kg/m2 (with obesity related comorbidities) * Patients willing and able to comply with study requirements for follow-up * Patients who previously underwent bariatric surgery who failed to lose the expected weight or regained weight * Individuals 18 years old or older are included Exclusion Criteria: * Pre-existing esophageal stenosis/stricture preventing advancement of an endoscope during screening/baseline Esophagogastroduodenoscopy (EGD) * Esophageal, gastric or duodenal malignancy * Severe medical comorbidities precluding endoscopy, or limiting life expectancy to less than 2 years in the judgment of the endoscopist * Uncontrolled coagulopathy or inability to be off anticoagulation or anti-platelet medication (ASA, Plavix) for 1 week prior to and 2 weeks after each endoscopy * Known portal hypertension, visible esophageal or gastric varices, or history of esophageal varices * General poor health, multiple co-morbidities placing the patient at risk, or otherwise unsuitable for trial participation at the discretion of the investigator * Pregnant or planning to become pregnant during period of study participation * Patient refuses or is unable to provide written informed consent * Prior surgical or endoscopic anti-reflux procedure * Patients who are unwilling or unable to comply with the follow-up study schedule