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COMPLETED
NCT05521074
NA

Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD

Sponsor: Massachusetts General Hospital

View on ClinicalTrials.gov

Summary

The investigators want to learn more about how human beings learn not to fear and the impact of changing the fear network in the brain using transcranial Direct Current Stimulation (tDCS) in individuals with obsessive compulsive disorder (OCD). The investigators hope this study will help us understand how future treatments can help patients with OCD better control unwanted fear.

Official title: Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD: Towards Rational Design of Combination Therapies

Key Details

Gender

All

Age Range

18 Years - 60 Years

Study Type

INTERVENTIONAL

Enrollment

86

Start Date

2022-09-15

Completion Date

2025-07-31

Last Updated

2026-09-04

Healthy Volunteers

No

Interventions

DEVICE

Active tDCS

The investigators will use commercially available tDCS equipment (Neuroelectrics©, Barcelona, Spain). The cathode will be placed over the pre-SMA using the 10-20 EEG system and the anode will be on the right deltoid.

DEVICE

Sham tDCS

The investigators will use commercially available tDCS equipment (Neuroelectrics©, Barcelona, Spain). The cathode will be placed over the pre-SMA using the 10-20 EEG system and the anode will be on the right deltoid. tDCS will not be active in this condition.

Locations (1)

Massachusetts General Hospital

Boston, Massachusetts, United States