Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
ACTIVE NOT RECRUITING
NCT05523479
NA

The Maximizing Extubation Outcomes Through Educational and Organizational Research (METEOR) Trial

Sponsor: University of Pittsburgh

View on ClinicalTrials.gov

Summary

The METEOR Trial will compare four implementation strategies-traditional online education, protocol-directed care, interprofessional education, and a combination of protocol-directed care and interprofessional education-to test the hypotheses that interprofessional education is superior to traditional online education as an implementation strategy in the intensive care unit (ICU) and the benefits of interprofessional education are increased when interprofessional education is paired with a clinical protocol. Additionally, the trial will also test the hypothesis that preventive post-extubation NIV for high-risk patients and preventive post-extubation HFNC for low-risk patients are both superior to current clinical practice (i.e., conventional post-extubation oxygen therapy).

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

13018

Start Date

2023-03-01

Completion Date

2026-04

Last Updated

2026-02-18

Healthy Volunteers

No

Interventions

BEHAVIORAL

Traditional online education

A 30-60 minute, online, interactive, educational video that is customized to each provider type and offered with provider-specific continuing education credits

BEHAVIORAL

Interprofessional education

Interprofessional education (IPE) consists of both classroom-based IPE and just-in-time IPE. In classroom-based IPE, a trained physician educator with content expertise who works in the ICU leads a 60-to-90-minute, in-person, IPE workshop consisting of a 30-minute didactic session and a 30-to-60-minute small group session, during which participants work together to apply the content to authentic cases. The workshops, which are designed according to modern principles of adult learning and IPE, present the rationale and evidence supporting the preventive, post-extubation therapies. They are specifically designed to foster authenticity, reinforce role identity, and relate the content to life experience. In just-in-time IPE, trained local champions meet with the interprofessional ICU team each morning to identify eligible patients and, as needed, briefly review the evidence supporting proper use of the assigned preventive, post-extubation strategy.

BEHAVIORAL

Clinical protocol

An "adequately explicit" protocol provides specific rules for use of the preventive, post-extubation therapy based on patient data. A "ready-to-customize" version of the protocol with instructions to work with key local stakeholders to revise the protocol, accounting for local needs and resources, is provided. After local customization, a local champion then disseminates the protocol based on local practices.

OTHER

Risk-stratified preventive post-extubation noninvasive ventilation (NIV) or high-flow nasal cannula oxygen (HFNC)

Preventive post-extubation NIV for high-risk patients and preventive post-extubation HFNC for low-risk patients

OTHER

Preventive post-extubation high-flow nasal cannula oxygen (HFNC)

Preventive post-extubation HFNC for all eligible patients (without risk stratification)

Locations (15)

UPMC Carlisle

Carlisle, Pennsylvania, United States

UPMC Hanover

Hanover, Pennsylvania, United States

UPMC Harrisburg

Harrisburg, Pennsylvania, United States

UPMC Community Osteopathic

Harrisburg, Pennsylvania, United States

UPMC West Shore

Mechanicsburg, Pennsylvania, United States

UPMC East

Monroeville, Pennsylvania, United States

UPMC Jameson

New Castle, Pennsylvania, United States

University of Pittsburgh

Pittsburgh, Pennsylvania, United States

UPMC Magee-Womens Hospital

Pittsburgh, Pennsylvania, United States

UPMC Presbyterian

Pittsburgh, Pennsylvania, United States

UPMC St. Margaret

Pittsburgh, Pennsylvania, United States

UPMC Mercy

Pittsburgh, Pennsylvania, United States

UPMC Shadyside

Pittsburgh, Pennsylvania, United States

UPMC Passavant

Pittsburgh, Pennsylvania, United States

UPMC Memorial

York, Pennsylvania, United States