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Noninvasive Brain Stimulation to Enhance Reading Comprehension Ability in Adults
Sponsor: Vanderbilt University
Summary
The goal of this project is to address the urgent need for effective, scalable adult literacy interventions by integrating breakthroughs in two separate fields: 1.) the brain network science of resilience to reading disorders and 2.) high-definition non-invasive brain network stimulation. This study will first establish the efficacy of a novel, noninvasive stimulation protocol on reading behavior and brain metrics; then will determine how stimulation-induced effects interact with baseline reading comprehension ability; and lastly, will identify whether stimulation-induced effects are more clinically-beneficial than canonical behavioral interventions. Results may change the foundation for how we treat low adult literacy, and have the potential for wider reaching impacts on non-invasive stimulation protocols for other clinical disorders.
Official title: Bridging the Gap Between Brain Network Science and High-definition Non-invasive Brain Stimulation to Develop a Scalable Adult Literacy Intervention
Key Details
Gender
All
Age Range
18 Years - 40 Years
Study Type
INTERVENTIONAL
Enrollment
100
Start Date
2022-11-07
Completion Date
2026-09-10
Last Updated
2025-08-01
Healthy Volunteers
Yes
Conditions
Interventions
Sham intervention
Use of the non-invasive brain stimulation device to simulate peripheral experience of stimulation without actually stimulating the brain.
RLN real non-invasive brain stimulation intervention
Real non-invasive brain stimulation to the left angular gyrus using transcranial alternating current stimulation (tACS).
RLN and CCN real non-invasive brain stimulation intervention
Real non-invasive brain stimulation to the left dorsolateral prefrontal cortex and left angular gyrus using transcranial alternating current stimulation (tACS).
Locations (1)
Vanderbilt University Medical Center
Nashville, Tennessee, United States