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Longitudinal Multimodal Response Assessment During Neoadjuvant Treatment of Rectal Cancer
Sponsor: Jena University Hospital
Summary
This pilot study aims to trial multimodal early response assessment to enable therapy adaptions in the context of non-operative therapy strategies of locally advanced rectal cancer (LARC) for development of a non-invasive response prediction model.
Official title: Planning Adaptive Treatment by Longitudinal Response Assessment Implementing MR Imaging, Liquid Biopsy and Analysis of Microenvironment During Neoadjuvant Treatment of Rectal Cancer (PRIMO)
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
40
Start Date
2022-11-30
Completion Date
2030-09-30
Last Updated
2025-09-08
Healthy Volunteers
No
Interventions
Blood sample
longitudinal blood samples for CTC monitoring
MRI scan
longitudinal MRI scans (non-contrast enhanced)
Locations (1)
Department of Radiotherapy and Radiation Oncology, Jena University Hospital
Jena, Germany