Clinical Research Directory

Inclusion Criteria: Patients: * Patient must be able to read and sign the informed consent form * Stable prophylactic medication for 2 months prior to MRI * At leat one of the two criteria applies: * Patients diagnosed with migraine (with or without aura, episodic or chronic). Diagnosis is ensured by clinical interview (at least 8 weeks prior to MRI). Also, patients complete a migraine questionnaire (HARDSHIP) (at least 8 weeks before MRI). Migraine frequency ≥ 2 migraine attacks/month. * Patients with drug resistent epilepsy accroding to ILAE crtieria * Patients with diagnoses of Visual snow syndrome Healthy participants; * No migraine (validated by questionnaire) or epilepsy * Participants must be able to read and sign the informed consent form Exclusion Criteria: * Treatment of migraine disease with Botox within \< 4 months before baseline and during the study period * Pregnant or breastfeeding women * Intention during the course of the trial to become pregnant * Women with bilateral ovariectomy, with or without hysterectomy, and postmenopausal women (\>2 years of age) are not considered childbearing. * Other clinically significant comorbidities (e.g., renal insufficiency, hepatic dysfunction, cardiovascular disease, etc.), * Known or suspected noncompliance with the protocol, drug or alcohol abuse, * Patient's inability to follow trial procedures, e.g., due to language problems, mental illness, dementia, etc., * Prior participation in the clinical trial * Enrolment of the investigator, his/ her family members, employees and other dependent persons of the test personnel * Metallic objects in the body (e.g., splinters, MR incompatible implants). * Pacemaker * Claustrophobia * Obesity (body mass index \> 35 kg/m2)