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OAT-GUT-BRAIN: Effects of Oats and Rice on Comprehensive Health of Metabolically Challenged Individuals
Sponsor: University of Turku
Summary
The overall objective of this research entity is to reveal the comprehensive health impact of oats in metabolically challenged individuals in a 6-week intervention, compared to that of rice. This is achieved by investigation of the lipids, short-chain fatty acids, inflammation markers and antioxidant status from plasma, fecal microbiome, and plasma metabolome. Additionally the effect of the 6-week diet on postprandial glycemia and postprandial satiety and vitality are investigated.
Official title: OAT-GUT-BRAIN: Comprehensive Health Effects of Long-term Consumption of Oats in Metabolically Challenged Volunteers - Gut-mediated Metabolomics and Vitality
Key Details
Gender
All
Age Range
30 Years - 68 Years
Study Type
INTERVENTIONAL
Enrollment
72
Start Date
2022-09-12
Completion Date
2027-12
Last Updated
2026-03-31
Healthy Volunteers
No
Interventions
Dietary intervention
Changes in dietary intake, metabolism, fecal microbiome, vitality and perceived health after a 6-week consumption of oat or rice-rich low-gluten diet.
Postprandial meal test
Postprandial changes after the 6-week consumption of either oat or rice-rich low-gluten diet, including blood markers, microbiome, satiety, recovery and vitality.
Locations (2)
Food Sciences, Department of Life Technologies, University of Turku
Turku, Turku, Finland
Institute of Public Health and Clinical Nutrition, University of Eastern Finland
Kuopio, Finland