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COMPLETED
NCT05528172
PHASE3

A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery

Sponsor: Kowa Research Institute, Inc.

View on ClinicalTrials.gov

Summary

The purpose of this study is to assess the safety and efficacy of K-321 in subjects after cataract surgery

Official title: A Double-Masked, Randomized, Placebo-Controlled, Parallel-Group, 12-Week Treatment and 14-week Extension, Phase 3 Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

330

Start Date

2022-08-04

Completion Date

2023-06-22

Last Updated

2026-08-06

Healthy Volunteers

No

Interventions

DRUG

Ripasudil

K-321 ophthalmic solution

DRUG

Placebo

Placebo ophthalmic solution

Locations (45)

Cornea and Cataract Consultants of Arizona

Phoenix, Arizona, United States

Schwartz Laser Eye Center

Scottsdale, Arizona, United States

Inland Eye Specialists

Hemet, California, United States

United Medical Research Institute

Inglewood, California, United States

Alvarado Eye Associates

La Mesa, California, United States

SoCal Eye Physicians and Associates

Long Beach, California, United States

Visionary Research Institute

Newport Beach, California, United States

Pendleton Eye Center

Oceanside, California, United States

North Bay Eye Associates

Petaluma, California, United States

Martel Eye Medical Group

Rancho Cordova, California, United States

Premiere Practice Management, LLC

Torrance, California, United States

Wolstan and Goldberg Eye Associates

Torrance, California, United States

Icon Eye Care

Grand Junction, Colorado, United States

Eye Associates of Fort Myers

Fort Myers, Florida, United States

Levenson Eye Associates

Jacksonville, Florida, United States

International Research Center

Tampa, Florida, United States

Clayton Eye Clinical Research, LLC

Morrow, Georgia, United States

Durrie Vision

Overland Park, Kansas, United States

Eye Care Institute/Butchertown Clinical Trials

Louisville, Kentucky, United States

Maine Eye Center

Portland, Maine, United States

Fraser Eye Care Center

Fraser, Michigan, United States

Silverstein Eye Centers

Kansas City, Missouri, United States

Tekwani Vision Center

St Louis, Missouri, United States

Ophthalmology Associates

St Louis, Missouri, United States

Ophthalmology Consultantants, Ltd.

St Louis, Missouri, United States

Comprehensive Eye Care, Ltd.

Washington, Missouri, United States

Vance Thompson Vision-MT

Bozeman, Montana, United States

Vance Thompson Vision- NE

Omaha, Nebraska, United States

Wellish Vision Institute

Las Vegas, Nevada, United States

Center for Sight

Las Vegas, Nevada, United States

NYU Grossman School of Medicine

New York, New York, United States

Seeta Eye Center

Poughkeepsie, New York, United States

Vance Thompson Vision ND

West Fargo, North Dakota, United States

Cincinnati Eye Institute

Cincinnati, Ohio, United States

Cincinnati Eye Institute

Mason, Ohio, United States

Eye Care Specialists

Kingston, Pennsylvania, United States

Vance Thompson Vision

Sioux Falls, South Dakota, United States

Keystone Research

Austin, Texas, United States

Hill Country Eye Center

Cedar Park, Texas, United States

Louis M. Alpern, M.D., M.P.H.,P.A.

El Paso, Texas, United States

Houston Eye Associates

Houston, Texas, United States

Lake Travis Eye & Laser Center

Lakeway, Texas, United States

DCT-Shah Research, LLC dba Discovery Clinical Trials

Mission, Texas, United States

Terry Eye Associates

San Antonio, Texas, United States

Centro Oftalmologico Metropolitano

San Juan, Puerto Rico