Clinical Research Directory

Inclusion Criteria: * Male and female subject between 6 and 15 years-old. * Express informed consent f by at least one of the parents or legal representative, and oral consent of the child. * A confirmed K-SADS DSM-5 diagnosis of ADHD, ODD, CD, mood/anxiety disorder or DMDD, or a clinical diagnosis of IED. The request of a concomitant mental disorder allows to restrict this intervention to a clinical population. * A Parental-rated ARI total score of 4 or above at baseline. * A Clinical Global Impression-Severity score (CGI-S) of 4 or above (=at least moderately ill). * Persistence of irritability symptoms 6 month or above at baseline (this avoids including children with transitory irritability). * stable treatment regimen (pharmacological and non-pharmacological) for 2 weeks prior to inclusion and during the trial * RESIST-QUAL : Same inclusion criteria as above with specific informed consent form signed by the participating parent. Exclusion Criteria: * Unavailability of parents or legal representative during the study period. * Subjects with a DSM-5 diagnosis (clinical presentation or history) that is consistent with Schizophrenia or psychotic disorders or acute manic episodes. * Diagnosis of Autism Spectrum Disorder (ASD) in patients who are non-verbal and with IQ lower than 70. * Known or estimated IQ\<70 or clinical diagnosis of intellectual disability. * Subjects with severe irritability that are better accounted for by another factor, e.g.: general medical condition(s) or direct effect of a substance (i.e., medication, illicit drug use), as determined by the clinical judgment of the investigator, or related to child abuse and/or neglect. * absence of informed consent give by at least one of the parents or legal representatives, and oral consent of the child * inability to speak and comprehend French * deemed unable to comply with the trial protocol * participation in a structured parent program during the last 6 months