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Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity
Sponsor: University of Mississippi Medical Center
Summary
This study will look at whether accounting for the amount of pressure generated by the chest wall and abdomen in a obese patient, using a measurement called transpulmonary pressure, can help shorten the amount of time patients spend on the ventilator. By decreasing the amount of time patients spend on the ventilator, they are less likely to develop complications such as infections, weakness or more procedures.
Official title: Transpulmonary Pressure Guided Weaning From Invasive Mechanical Ventilation in Obese Patients With Respiratory Failure
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
4
Start Date
2022-04-11
Completion Date
2026-04-14
Last Updated
2026-05-14
Healthy Volunteers
No
Conditions
Interventions
transpulmonary pressure guided positive end expiratory pressure
Positive end expiratory pressure will be titrated to achieve a transpulmonary pressure of 0-2 cm H2O
standard positive end expiratory pressure
Positive end expiratory pressure will be set to a standard 5-8 cm H2O by the clinician for spontaneous breathing trials
Locations (1)
University of Mississippi Medical Center
Jackson, Mississippi, United States