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RECRUITING
NCT05531240
NA

Transurethral Prostate Resection (TURP) vs. Prostate Artery Embolization (PAE)

Sponsor: Uppsala University

View on ClinicalTrials.gov

Summary

This study focuses on the treatment of benign prostatic hyperplasia which causes lower urinary tract symptoms. The purpose of the research project is to evaluate PAE in terms of both medical and health economic outcomes. To evaluate whether there are any differences in effect (IPSS), complications, costs and perceived quality of life compared with TUR-P.

Official title: Transurethral Prostate Resection (TURP) vs. Prostate Artery Embolization (PAE): Open Multicentric Randomized Study for Evaluation of Outcomes, Complications, and Health Economics

Key Details

Gender

MALE

Age Range

45 Years - Any

Study Type

INTERVENTIONAL

Enrollment

104

Start Date

2022-10-01

Completion Date

2029-12

Last Updated

2026-10-02

Healthy Volunteers

No

Interventions

PROCEDURE

Prostate Artery Embolization

Prostate Artery Embolization (PAE) is performed by experienced interventional radiologists. The method involves catheterization of the prostate vessels superselectively with two to three French microcatheters. PAE is performed with microspheres of 250 to 400 µm in size.

PROCEDURE

Transurethral Prostate Resection (TURP)

Under general/regional anesthesia, a resectoscope is inserted into the urethra that carries an electric metal loop (monopolar or bipolar diathermy) that is used to cut and extract the prostate tissue.

Locations (4)

Helsingborgs Hospital

Helsingborg, Region Skånes, Sweden

Mälarsjukhuset

Eskilstuna, Region Sörmland, Sweden

Lasarettet i Enköping

Enköping, Region Uppsala, Sweden

Region Vastmanland Hospital

Västerås, Västmanland County, Sweden