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RECRUITING
NCT05533060

Clinical and Molecular Biological Data Collection and Analysis in Patients With TBI

Sponsor: Shanghai 6th People's Hospital

View on ClinicalTrials.gov

Summary

Clinical evaluation is crucial in the clinical diagnosis, treatment, and prognosis prediction in patients with traumatic brain injury (TBI). However, the existing evaluation systems are not perfect, because many factors are not taken into account, for example, there is a lack of molecular diagnostic criteria for evaluating patients with TBI. We attempt to collect the patient's clinical data and combine it with neuroimaging, as well as molecular biomarkers generated by single-cell sequencing to assess their neurological status and outcome. The clinical and molecular data collection and analysis will be helpful to evaluate the patient's neurological condition and predict the patient's outcome more accurately.

Official title: Clinical and Molecular Biological Data Collection and Analysis in Patients With Traumatic Brain Injury (TBI)

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

200

Start Date

2022-09-01

Completion Date

2027-12-30

Last Updated

2025-05-06

Healthy Volunteers

No

Interventions

OTHER

No intervention

patients in the groups are treated surgically and brain tissue, CSF, and blood samples, as well as clinical data, neuroimaging data are collected

Locations (1)

Shanghai 6th People's Hospital

Shanghai, China