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Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health
Sponsor: University of Florida
Summary
Previous studies have shown that polyphenol-rich foods can positively affect cognitive functions, memory, and mood in humans. We hypothesize that both acute and chronic intake of muscadine wine polyphenols will improve cognitive performance and mood through regulating the HPA axis, alleviating inflammation and oxidative stress, and/or inhibiting monoamine oxidase activities
Official title: Acute and Chronic Impacts of Muscadine Wine Polyphenols on Cognition, Memory, Mood, and Anxiety in Adults Over 50 Years of Age
Key Details
Gender
All
Age Range
50 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
25
Start Date
2023-08-30
Completion Date
2026-12
Last Updated
2025-06-12
Healthy Volunteers
Yes
Conditions
Interventions
Muscadine Wine Polyphenol
dealcoholized muscadine wine with alcohol content \<0.5% with addition of 50ppm of sodium metabisulfite for preservation
Placebo
this placebo beverage is formulated with matching sugar and organic acid content to the muscadine wine polyphenol. Food coloring is added to match the color of the intervention. 50ppm of sodium metabisulfite for preservation
Locations (1)
Food Science and human nutrition department at University of Florida
Gainesville, Florida, United States