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Ketorolac Intravenous Regional Analgesia in Lower Limb Surgeries
Sponsor: Mansoura University
Summary
Tourniquet, a compressing device, otherwise its use in intravenous regional anesthesia, is commonly used in particular orthopedic surgeries. From the previous documented effectiveness and safety of intravenous (IV) administration of ketorolac in the circulatory-isolated limb as a part of intravenous regional anesthesia; we hypothesized that in orthopedic surgeries done with tourniquet, intravenous (IV) administration of ketorolac after tourniquet inflation, will act as intravenous regional analgesia. So, it will prolong the postoperative analgesic duration as a primary outcome.
Official title: Ketorolac for Intravenous Regional Analgesia in Lower Limb Orthopedic Surgeries Under Spinal Anesthesia: A Randomized Control Study
Key Details
Gender
All
Age Range
19 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
76
Start Date
2022-11-01
Completion Date
2027-12-30
Last Updated
2026-02-17
Healthy Volunteers
No
Conditions
Interventions
Ketorolac
After confirmation of circulatory isolation of the operated limb by the inflated tourniquet, 30 mg ketorolac tromethamine diluted in normal saline in a total volume of 50 ml will be injected
Control
After confirmation of circulatory isolation of the operated limb by the inflated tourniquet, 50 ml normal saline without drugs will be injected
Locations (1)
Mansoura University Hospitals
Al Mansurah, Egypt