Clinical Research Directory

Inclusion Criteria: 1. Ages 18 and older 2. Idiopathic Parkinson's disease Hoehn and Yahr stage I 3. Fluent in English 4. Appropriate social support if required during an off state. 5. Comfortable with technology; can use a computer, check email, and access the internet; can initiate and engage in a virtual meeting for training and monitoring purposes. 6. Feels comfortable going off PD related medication during in person study visits 7. Lives in the United States Exclusion Criteria: 1. Any significant neuro-psychiatric problems, including acute confusional state, ongoing psychosis, or suicidal tendencies 2. Any current drug or alcohol abuse. 3. Participation in another drug, device, or biologics trial concurrently or within the preceding 30 days. Any other trial participation should be approved by the Principal Investigators. 4. Pregnancy, breast-feeding or wanting to become pregnant 5. Physical limitations unrelated to PD that would affect motor ratings 6. Craniotomy 7. Brain surgery 8. Patient is unable to communicate properly with staff (i.e., severe speech problems) 9. Excessive drooling 10. A type of hair style that would impede the use of an EEG cap 11. Sensory abnormalities of the fingertips 12. Nasal dysfunction unrelated to smell loss