Clinical Research Directory

Inclusion Criteria: * Postmenopausal women (\>2 years since last menses) * Body mass index (25-45 kg/m2) * Agree to be randomly assigned to consume food for ≤ 9 hours/day or ≥12 hours/day * Must attend on-site visits (about 10) in New Brunswick, NJ, USA (transportation/reimbursement for travel not included) Exclusion Criteria: * Participants with \>5% weight loss in the past 6 months or extreme dietary/physical activity habits * An inability to follow the experimental intervention or to perform the required specimen collections * Antibiotic use in the past 2 months * Current diagnosis, or history of cancer in past 3 years * History of surgical procedure for weight loss in the past 3 years * Current diagnosis or history of bone diseases, type I or II diabetes, gastrointestinal disease, hyperparathyroidism, untreated thyroid disease, significant immune, hepatic, cardiac, or renal disease * Uncontrolled hypertension or hyperlipidemia in abnormal ranges * Regular use of medications that affect bone metabolism, including bisphosphonates or hormone replacement. * A colonoscopy within the past 2 months * Alcohol or illicit drug abuse * Current smoker or having quit smoking in the past 3 months * Shift work * Participation in another clinical research trial which may interfere with the results of this study.