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RECRUITING
NCT05551416

The EpiGASTRIC/EDGAR Project: New Strategies for the Early Detection and Prevention of Gastric Cancer

Sponsor: EDUARDO ALBENIZ

View on ClinicalTrials.gov

Summary

This study is a multicenter, prospective cohort study, which are planned to enroll at least 600 patients who diagnosed the primary gastric cancer (GC); around 50 patients with premalignant gastric lesions (PGLs) and early gastric neoplasias (EGC) treated by endoscopy resection; and no less than 600 healthy normal cohort participants, for more than 18 months in the Spanish population. All participants who enrolled in this registry will be questioned by the life habits survey; and clinical data and biological samples of these participants were analyzed in order to look for new diagnostic tools. The aim of this study is to evaluate clinical, endoscopic and molecular approaches to identify individuals with high-risk of GC. Thus, it would be allow the adoption of preventive measures to reduce mortality through early detection and/or the reduction of its incidence.

Official title: Research and Development of New Strategies for the Early Detection and Prevention of Gastric Cancer in the Spanish Population: EpiGASTRIC/EDGAR Project.

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

1200

Start Date

2021-09-09

Completion Date

2026-12-31

Last Updated

2023-10-24

Healthy Volunteers

No

Interventions

OTHER

Identification of risk factors

Demographics, life habits and risk factors studies

OTHER

Characterization of premalignant gastric lesions

Identification and characterization of premalignant gastric lesions through high definition endoscopic study. Concordance between endoscopic and histological classifications

OTHER

Identification of biomarkers

Multiomic studies

OTHER

Identification of gastric cancer hereditary predisposition

Genomic studies for the identification of individuals with hereditary GC predisposition

Locations (15)

Hospital Comarcal de Inca

Palma de Mallorca, Balearic Islands, Spain

Hospital de Llevant

Porto Cristo, Balearic Islands, Spain

Hospital General de Granollers

Granollers, Barcelona, Spain

Consorci Sanitari de Terrassa

Terrassa, Barcelona, Spain

Hospital Santos Reyes

Aranda de Duero, Burgos, Spain

Hospital de Mérida

Mérida, Extremadura, Spain

Hospital Universitario de Ourense

Ourense, Galicia, Spain

Hospital Puerta de Hierro

Majadahonda, Madrid, Spain

Hospital Universitario de Navarra

Pamplona, Navarre, Spain

Hospital Universitario Central de Asturias

Oviedo, Principality of Asturias, Spain

Hospital Clínic de Barcelona

Barcelona, Spain

Hospital Universitario de Burgos

Burgos, Spain

Hospital Josep Trueta

Girona, Spain

Hospital Clínico Universitario Lozano Blesa

Zaragoza, Spain

Hospital Universitario Miguel Servet

Zaragoza, Spain