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The EpiGASTRIC/EDGAR Project: New Strategies for the Early Detection and Prevention of Gastric Cancer
Sponsor: EDUARDO ALBENIZ
Summary
This study is a multicenter, prospective cohort study, which are planned to enroll at least 600 patients who diagnosed the primary gastric cancer (GC); around 50 patients with premalignant gastric lesions (PGLs) and early gastric neoplasias (EGC) treated by endoscopy resection; and no less than 600 healthy normal cohort participants, for more than 18 months in the Spanish population. All participants who enrolled in this registry will be questioned by the life habits survey; and clinical data and biological samples of these participants were analyzed in order to look for new diagnostic tools. The aim of this study is to evaluate clinical, endoscopic and molecular approaches to identify individuals with high-risk of GC. Thus, it would be allow the adoption of preventive measures to reduce mortality through early detection and/or the reduction of its incidence.
Official title: Research and Development of New Strategies for the Early Detection and Prevention of Gastric Cancer in the Spanish Population: EpiGASTRIC/EDGAR Project.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
1200
Start Date
2021-09-09
Completion Date
2026-12-31
Last Updated
2023-10-24
Healthy Volunteers
No
Interventions
Identification of risk factors
Demographics, life habits and risk factors studies
Characterization of premalignant gastric lesions
Identification and characterization of premalignant gastric lesions through high definition endoscopic study. Concordance between endoscopic and histological classifications
Identification of biomarkers
Multiomic studies
Identification of gastric cancer hereditary predisposition
Genomic studies for the identification of individuals with hereditary GC predisposition
Locations (15)
Hospital Comarcal de Inca
Palma de Mallorca, Balearic Islands, Spain
Hospital de Llevant
Porto Cristo, Balearic Islands, Spain
Hospital General de Granollers
Granollers, Barcelona, Spain
Consorci Sanitari de Terrassa
Terrassa, Barcelona, Spain
Hospital Santos Reyes
Aranda de Duero, Burgos, Spain
Hospital de Mérida
Mérida, Extremadura, Spain
Hospital Universitario de Ourense
Ourense, Galicia, Spain
Hospital Puerta de Hierro
Majadahonda, Madrid, Spain
Hospital Universitario de Navarra
Pamplona, Navarre, Spain
Hospital Universitario Central de Asturias
Oviedo, Principality of Asturias, Spain
Hospital Clínic de Barcelona
Barcelona, Spain
Hospital Universitario de Burgos
Burgos, Spain
Hospital Josep Trueta
Girona, Spain
Hospital Clínico Universitario Lozano Blesa
Zaragoza, Spain
Hospital Universitario Miguel Servet
Zaragoza, Spain