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TERMINATED
NCT05552443
PHASE4

A Study of Intrathecal Hydromorphone for Pediatric Idiopathic Scoliosis Repair

Sponsor: Mayo Clinic

View on ClinicalTrials.gov

Summary

The purpose of this study is to identify a dose of intrathecal hydromorphone (opioid pain medicine) that optimizes pain control but minimizes side effects historically seen with this class of pain medications.

Official title: Identification of the Optimal Analgesic Dose of Intrathecal Hydromorphone for Pediatric Patients Undergoing Posterior Spine Surgery for Idiopathic Scoliosis

Key Details

Gender

All

Age Range

10 Years - 17 Years

Study Type

INTERVENTIONAL

Enrollment

31

Start Date

2023-03-23

Completion Date

2024-12-31

Last Updated

2026-05-14

Healthy Volunteers

No

Conditions

Interventions

DRUG

Hydromorphone 2.5 mcg/kg

2.5 mcg/kg intrathecal

DRUG

Hydromorphone 2.75 mcg/kg

2.75 mcg/kg intrathecal

DRUG

Hydromorphone 3 mcg/kg

3 mcg/kg intrathecal

DRUG

Hydromorphone 3.25 mcg/kg

3.25 mcg/kg intrathecal

DRUG

Hydromorphone 3.5 mcg/kg

3.5 mcg/kg intrathecal

DRUG

Hydromorphone 4 mcg/kg

4 mcg/kg intrathecal

DRUG

Hydromorphone 4.5 mcg/kg

4.5 mcg/kg intrathecal

DRUG

Hydromorphone 5 mcg/kg

5 mcg/kg intrathecal

DRUG

Hydromorphone 5.5 mcg/kg

5.5 mcg/kg intrathecal

DRUG

Hydromorphone 6 mcg/kg

6 mcg/kg intrathecal

DRUG

Hydromorphone 6.5 mcg/kg

6.5 mcg/kg intrathecal

DRUG

Hydromorphone 7 mcg/kg

7 mcg/kg intrathecal

Locations (1)

Mayo Clinic Rochester

Rochester, Minnesota, United States