Clinical Research Directory

Inclusion Criteria: 1. Read the patient information bulletin on the study and signed the patient consent form 2. Adult patient (over 18-year-old) 3. Suitable and in need for surgical lower limb operation listed in the indications of this study that requires fastening of bone structures with screws (or an alternative attachment method) in the ankle or foot area, according to a statement of the investigator surgeon 4. Ability to fill in questionnaires. 5. Willingness to comply with rehabilitation instructions. 6. Availability for follow-up visits. Exclusion Criteria: 1. Active infection 2. Patient conditions including limited blood supply (e.g. patients with severe circulatory disorder of the lower limb 3. Patient conditions including insufficient quality or quantity of bone (diagnosed osteoporosis, conditions causing secondary osteoporosis e.g. diabetes, rheumatism, eating disorder) 4. Patient conditions where patient cooperation cannot be guaranteed (alcohol use, drug abuse etc.) 5. High-load bearing indications (e.g., diaphyseal fractures of long bones) unless used in conjunction with traditional rigid fixation 6. Patients with significant neuropathy 7. Pregnancy 8. Patients who refuse to participate 9. Lower limb tumor or metastasis 10. Complex Regional Pain Syndrome (CRPS) in operated foot