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Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
Sponsor: University of Alabama at Birmingham
Summary
The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS, and finally 3) whether different SCS waveforms elicits stimulus-evoked compound action potentials (ECAPs) in spinal cord and at the cortex (electroencephalography, and magnetoenchphalography).
Key Details
Gender
All
Age Range
18 Years - 89 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2022-08-02
Completion Date
2030-05-01
Last Updated
2025-08-28
Healthy Volunteers
No
Conditions
Interventions
Permanent Epidural Spinal Cord Stimulation
Permanent Spinal Cord Stimulation implanted in participants undergoing routine care for management of chronic neuropathic pain.
Locations (1)
University of Alabama at Birmingham
Birmingham, Alabama, United States