Clinical Research Directory

Inclusion Criteria: * Adult men and women aged at least 18 years * Scheduled for diagnostic CAG due to suspected obstructive coronary artery disease Exclusion Criteria: * Presence of contra-indications for the use of clopidogrel (hypersensitivity or known allergy to clopidogrel, severe liver insufficiency, resent or active pathological bleeding, patients known to be poor CYP2C19 metabolizers, patients using pharmacological CYP2C19 inhibitors and inducers) * Patients using clopidogrel for other reasons than the scheduled diagnostic CAG (e.g. due to previous stroke) * Patients using P2Y12 inhibitors other than clopidogrel (e.g. prasugrel, ticagrelor, cangrelor) * Patients using VKA (e.g. acenocoumarol, fenprocoumon) * Patients using DOAC/NOAC (e.g. apixaban, dabigatran, edoxaban, rivaroxaban) * Inability to give informed consent (e.g., language barrier) * Patients who have a documented mentioning of previous denial to any trial participation in the electronic patient dossier