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rTMS for Apathy Clinical Trial
Sponsor: Sunnybrook Health Sciences Centre
Summary
Apathy is a common, early, and disabling symptom in dementias and mild behavioural impairment such as Alzheimer's disease (AD) and is characterized by lack of interest and enthusiasm. Both repetitive transcranial magnetic stimulation (rTMS), a form of non-invasive brain stimulation, and methylphenidate, a medication, have been shown to improve apathy. This pilot study will investigate rTMS as a treatment for apathy in neurocognitive disorders and mild behavioural impairment in individuals receiving methylphenidate and individuals not receiving medication for apathy.
Official title: Repetitive Transcranial Magnetic Stimulation for Apathy Clinical Trial (REACT)
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2023-02-09
Completion Date
2025-12-01
Last Updated
2025-07-08
Healthy Volunteers
No
Conditions
Interventions
rTMS
repetitive transcranial magnetic stimulation
methylphenidate
methylphenidate
Locations (1)
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada