Clinical Research Directory

Inclusion Criteria: * Patient older than 50 years old * Patient requiring bilateral cataract surgery * Regular corneal astigmatism \>0.5D measured by MS-39 (SimK keratometry and regularity determined by the topography) for patients implanted with SYNTHESIS PLUS TORIC or Regular corneal astigmatism lower or equal to 0.5 D dioptres by MS-39 (SimK keratometry and regularity determined by the topography) for patients implanted with SYNTHESIS PLUS. * Expected postoperative astigmatism ≤ 0.75D diopter * Corneal astigmatism ≤4D * IOL spherical equivalent power requested between 15D and 25D * Signed informed consent * Availability, willingness and sufficient cognitive awareness to comply with examination procedures Non inclusion Criteria: * Patients with a potential postoperative visual acuity of less than 5/10, in particular due to degenerative visual disorders, poor retinal function or a damaged cornea. * Amblyopia with a visual acuity potential of less than 5/10 * IOL power needed outside the spherical equivalent diopter range: 15 to 25D * Difficulty for cooperation (distance from their home, general health condition) * Acute or chronic disease or illness that would increase risk or confound study results (e.g. diabetes mellitus (with retinopathy), immunocompromised, glaucoma etc…) * Irregular astigmatism * Subject with postoperative astigmatism, expected \> 0.75 D. * Any ocular comorbidity * History of ocular trauma or prior ocular surgery including refractive procedures * Capsule or zonular abnormalities that may affect postoperative centration or tilt of the lens (e.g. pseudoexfoliation syndrome, chronic Uveitis, Marfan's syndrome) * Patients with chronic uveitis * Pupil abnormalitis (non-reactive, tonic pupils, abnormally shaped pupils or pupils that do not dilate under mesopic/scotopic conditions, diameter (pupil\>4mm or \<2.5 mm in photopic conditions)) * Narrow anterior chambers (ACD ≤ 2.5 mm) * Any corneal pathology potentially affecting the topography (eg. Keratoconus), * Monophthalma patients * Phacodonesis Exclusion criteria: * Complicated surgery * Inability to place the intraocular lens safely at the location planned * Subjects with zonular laxity * Postoperative endophthalmitis