Clinical Research Directory

Inclusion Criteria: The subjects must meet all the following criteria to be eligible to participate in the clinical investigation: 1. Diagnosed MS according to revised McDonald criteria. 2. Give written informed consent. 3. Age 18-70 years. 4. Stable MS disease without attack within the last three months. 5. Ability to perform the walk tests: 1. 2-minute walk test, and 2. 25-Foot walk. 6. Self-reported spasticity in the most affected leg that would be subject to treatment at baseline with a score of ≥ 4, scored using the numeric rating scale (NRS) during the last 24 hours. 7. Pain and/or discomfort related to the spasticity described in inclusion criteria 6., over the last 7 days using the numeric rating scale (NRS). 8. Stable and unchanged treatment of spasticity and pain over the last month, as judged by the Investigator. 9. Stable and unchanged disease-modulating treatment for MS last 6 months, as judged by the Investigator. 10. Can self-manage study equipment. 11. Willingness and ability to comply with study procedures, visit schedules, and requirements. Exclusion Criteria: Subjects meeting any of the following criteria will not be permitted to participate in the clinical investigation: 1. Have spasticity due to a disease other than MS. 2. Pregnancy or planned pregnancy within the upcoming study period, up to 7 months (includes the optional extension part). 3. Have an ongoing infection that subjectively affects their MS state, as judged by the Investigator. 4. Have received botulinum toxin injection for spasticity within the last 4 months. 5. Have symptoms or illness that make it difficult to participate in the study, as judged by the Investigator. 6. Having planned surgery or other treatment within the coming study period of up to 7 months making it difficult to participate in the study, as judged by the Investigator. 7. Subjects with uncontrolled wound infections or infections in the skin of the treated leg.