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Cognitive Assessment and Brain Function Evaluation in Patients With Non-alcoholic Fatty Liver Disease
Sponsor: Yan Bi
Summary
The purpose of this study is to explore the relationship between Non-alcoholic fatty liver disease and cognitive impairment and evaluate the effect of metabolic surgery or lifestyle intervention on cognition.
Official title: The Cross-sectional and Longitudinal Study of Relationship Between Non-alcoholic Fatty Liver Disease and Cognitive Impairment
Key Details
Gender
All
Age Range
20 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
500
Start Date
2020-05-01
Completion Date
2025-09
Last Updated
2024-06-21
Healthy Volunteers
Yes
Interventions
Cognitive assessment, functional magnetic resonance imaging
Our study investigated cognitive function, MRI measures of brain structure and activation in patients undergoing liver biopsy. We aimed to evaluate the changes of cognition during the process of NAFLD and explore the association between brain alterations and cognition.
Locations (1)
at Division of Endocrinology, the Affiliated Drum Tower Hospital of Nanjing University
Nanjing, Jiangsu, China