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Cognitive Outcomes of Brain Stimulation As a Later-in-Life Treatment
Sponsor: University of Texas Southwestern Medical Center
Summary
This is a pilot study being done to attempt to improve episodic memory problems in persons with mild cognitive impairment (MCI). The pre-supplemental motor area (preSMA) and dorsal anterior cingulate cortex (dACC) have been shown to play a role in episodic memory and language retrieval. Prior studies have suggested that neurostimulation targeting this region can improve episodic memory and word recall. The purpose of this study is to examine the efficacy of high-definition transcranial direct current stimulation (HD-tDCS) to the preSMA/dACC region and its influence on word retrieval and other cognitive functions in patients with MCI. Entraining the preSMA/dACC circuit with 10 sessions of HD-tDCS will allow us to study whether neurostimulation may be an effective treatment.
Key Details
Gender
All
Age Range
55 Years - Any
Study Type
INTERVENTIONAL
Enrollment
27
Start Date
2023-05-01
Completion Date
2025-06-03
Last Updated
2026-06-12
Healthy Volunteers
No
Interventions
NeuroElectric StarStim
10 sessions of active stimulation (1 mA anodal HD-tDCS targeting preSMA/dACC for 20 min) across 2 weeks
Sham Treatment
Sham stimulation for 10 sessions over 2 weeks
Locations (1)
University of Texas Southwestern Medical Center
Dallas, Texas, United States