Tundra Space

Tundra Space

Clinical Research Directory

Browse clinical research sites, groups, and studies.

Back to Studies
COMPLETED
NCT05565638
NA

PROFAST Intervention in Precursor Multiple Myeloma

Sponsor: Dana-Farber Cancer Institute

View on ClinicalTrials.gov

Summary

This is a 4-month randomized trial of a prolonged nightly fasting intervention (PROFAST) in 40 overweight and obese individuals with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and smoldering waldenstrom macroglobulinemia (SWM). The purpose of this study is to understand if fasting for a prolonged period of time during the nighttime hours is a strategy to prevent overweight and obese individuals from developing blood cancer. Participants will be randomized into the following two groups: * Group A: PROFAST intervention for 4 months * Group B: Healthy Lifestyle Control group for 4 months

Official title: PROlonged Nightly FASTing for Obesity Reduction and Prevention of Disease Prevention in Precursor Multiple Myeloma (PROFAST)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

23

Start Date

2023-03-06

Completion Date

2025-08-04

Last Updated

2026-10-07

Healthy Volunteers

No

Interventions

BEHAVIORAL

Prolonged Fasting Intervention

promote a 14-hour fast during the nighttime hours

BEHAVIORAL

EDUCATION CONTROL

introductory session with a health coach and educational information will be provided. Participants will also receive one email and one text message per week with tips on healthy living

Locations (1)

Dana Farber Cancer Institute

Boston, Massachusetts, United States