Clinical Research Directory

Inclusion Criteria: Patient population: Age 18-55, * Confirmation of an anxiety disorder as identified by the PSWQ, * No known, current or history, of significant medical conditions that may affect or directly involve the neurological, cardiovascular or respiratory system (except anxiety and depression) * Non-smoker Healthy Volunteers: * Age 18-55 * No known, current or history, of significant medical conditions that may affect or directly involve the neurological, cardiovascular or respiratory system * Non-smoker Exclusion Criteria: * General MRI contraindications: pacemakers, defibrillating wires, implanted defibrillators, intracranial aneurysm clips, metallic foreign bodies in the eyes, pregnancy * History of significant neurological disease or illness that is not anxiety (e.g. Dementia, stroke) * Hemodynamically unstable conditions * Significant or uncontrolled arrhythmias * Severe pulmonary disease * Recent (\<90 days) myocardial infarction * Recent (\<90 days) surgery or coronary intervention * Consumption of caffeine (caffeinated beverages, coffee, tea, cocoa, chocolate) within 12h of the exam * Use of benzodiazepines or other short-acting anxiety medications (\<1 day)